Wars, riots, domestic violence, and international conflicts—it’s clear that the world is not at peace. But our internal worlds don’t have to mirror this external chaos. In this message, Dr. Stanley speaks of Jesus Christ as the Prince of Peace and explains how we can find inner contentment and true rest through a personal relationship with Him. Don’t let things like anger, lust, or bitterness steal your peace. Learn how to trust God and let Him calm your soul with His soothing presence.
聯合生物製藥(股)公司(聯生藥)今日宣布，美國FDA已同意其治療愛滋病抗體新藥UB-421在產生多重抗藥性之HIV-1感染者身上的臨床試驗: “A Multicenter, Single-Arm, 24-Week Study of UB-421 in Combination with Optimized Background Therapy (OBT) Regimen in Patients with Multi-Drug Resistant (MDR) HIV-1 Infection”。
Taipei, Taiwan, May 21, 2019 — United BioPharma (UBP) announced today that the company has obtained U,S. FDA’s approval to conduct a clinical trial with UB-421 in the USA, under the protocol entitled “A Multicenter, Single-Arm, 24-Week Study of UB-421 in Combination with Optimized Background Therapy (OBT) Regimen in Patients with Multi-Drug Resistant (MDR) HIV-1 Infection.”
Although HIV infection is manageable with a combination of two or more small molecule antiretroviral drugs, i.e. Antiretroviral Therapy (ART), a 4-8% small percentage of treated patients, who initially achieve viral suppression on effective ART, still develop persistent, low level plasma viremia. In other words, these patients have developed multi-drug resistance (MDR) to HIV and have exhausted treatment options, such that exposing to a high risk of AIDS complications and eventual progression to death.
In this study protocol, the eligible study participants will receive a single intravenous infusion of 5 mg/kg UB-421 plus their failing regimen in the first week, with a primary endpoint to achieve at least 0.5 log reduction in plasma viral load at the end of the week. The participants will then receive weekly 5 mg/kg UB-421 doses plus Optimized Background Therapy (OBT) Regimen for 24 weeks during the maintenance treatment period.
Imprisonment plus isolation plus a death sentence equals . . . joy? Wait, that can’t be right, can it? In this message, Dr. Stanley examines the apostle Paul’s triumphant joy in the face of dire circumstances. It may seem absurd, but as Christians, we’re enabled by the Holy Spirit to experience overflowing joy even when our lives only seem to be adding up to despair. Explore what it means to trade in superficial happiness for steadfast joy.